Veronica Jimenez Ortiz

Contact Information

Office: MH 307

Phone: 657-278-2477

Email:

vjimenezortiz@fullerton.edu

Veronica Jimenez Ortiz

AssOCIatE Professor

 

Program Coordinator, Undergraduate Research Training Initiative for Student Enhancement (U-RISE) Program (2023-2028)

Degrees

PhD, University of Chile, Santiago, Chile

MS, Juan Agustin Maza University, Mendoza, Argentina

BS, Juan Agustin Maza University, Mendoza, Argentina

Research Areas

Parasitic infections, role of ion channels in sensing and adaptation to environmental conditions in protozoan parasites; mechanosensation; electrophysiology.

Courses Regularly Taught

BIOL 462 General Parasitology, BIOL 362 Mammalian Physiology, BIOL 417 Advances in Cell Biology, BIOL 303 Intermediate Cell Biology

Publications

  • Jimenez, V; Mesones, S. Down the membrane hole: ion channels in protozoan parasites. PlosPathogens, 2022 Dec 29;18(12):e1011004.  doi: 10.1371/journal.ppat.1011004. eCollection 2022 Dec. PMID: 36580479.
  • Jimenez V, Miranda K, Augusto I. The old and the new about the contractile vacuole of Trypanosoma cruzi. J Eukaryot Microbiol. 2022 Aug 2;:e12939. doi: 10.1111/jeu.12939. Review. PubMed PMID: 35916682.
  • Dave N, Cetiner U, Arroyo D, Fonbuena J, Tiwari M, Barrera P, Lander N, Anishkin A, Sukharev S, Jimenez V. A novel mechanosensitive channel controls osmoregulation, differentiation, and infectivity in Trypanosoma cruzi. Elife. 2021 Jul 2;10. doi: 10.7554/eLife.67449.
  • Magallon J, Vu P, Reeves C, Kwan S, Phan K, Oakley-Havens CL, Rocha K, Jimenez V, Ramirez MS, Tolmasky ME. Amikacin potentiator activity of zinc complexed to a pyrithione derivative with enhanced solubility. Sci Rep. 2022 Jan 7;12(1):285. doi: 10.1038/s41598-021-04724-4.
  • Martinez J, Razo-Gutierrez C, Le C, Courville R, Pimentel C, Liu C, Fung SE, Tuttobene MR, Phan K, Vila AJ, Shahrestani P, Jimenez V, Tolmasky ME, Becka SA, Papp-Wallace KM, Bonomo RA, Soler-Bistue A, Sieira R, Ramirez MS. Cerebrospinal fluid (CSF) augments metabolism and virulence expression factors in Acinetobacter baumannii. Sci Rep. 2021 Feb 26;11(1):4737. doi: 10.1038/s41598-021-81714-6.
  • Reeves CM, Magallon J, Rocha K, Tran T, Phan K, Vu P, Yi Y, Oakley-Havens CL, Cedano J, Jimenez V, Ramirez MS, Tolmasky ME. Aminoglycoside 6'-N-acetyltransferase Type Ib [AAC(6')-Ib]-Mediated Aminoglycoside Resistance: Phenotypic Conversion to Susceptibility by Silver Ions. Antibiotics (Basel). 2020 Dec 31;10(1). doi: 10.3390/antibiotics10010029.
  • Barrera, P, Skorka, C; Boktor, M; Dave, N and Jimenez, V. Novel Calcium-Activated Potassium Channel Controls Membrane Potential and Intracellular pH in Trypanosoma cruzi.  Front. Cell. Infect. Microbiol., 15 January 2020. https://doi.org/10.3389/fcimb.2019.00464
  • Rodman, N; Martinez, J; Fung, S; Nakanouchi, J;  Myers, AL; Harris, C; Dang, E; Fernandez, J; Liu, C; Mendoza, A; Jimenez, V; Nikolaidis, N; Brennan, C;  Bonomo, RA; Sieira, R and Ramirez, MS. Human pleural fluid elicits pyruvate and phenylalanine metabolism in Acinetobacter baumannii to enhance cytotoxicity and immune evasion. Front. Microbiol., 17 July 2019. https://doi.org/10.3389/fmicb.2019.01581
  • Magallon, J; Chiem, K; Tran, T; Ramirez, MS; Jimenez, V and Tolmasky ME. 2019. Restoration of susceptibility to amikacin by 8-hydroxyquinoline analogs complexed to zinc. PLoS ONE 14(5): e0217602. https://doi.org/10.1371/journal.
  • Tran, T; Chiem, K; Jani, S; Arivett, B; Lin, D; Lad, R; Jimenez, V; Farone, M; Debevec, G; Santos, R; Giulianotti, M; Pinilla, C and Tolmasky, M. 2018. Identification of a Small Molecule Inhibitor of the Aminoglycoside 6'-N-Acetyltransferase Type Ib [AAC(6')-Ib] Using Mixture-Based Combinatorial Libraries. International Journal of Antimicrobial Agents. doi.org/10.1016/j.ijantimicag.2018.01.019.
  • Jimenez V, Docampo R. 2015. TcPho91 is a contractile vacuole phosphate sodium symporter that regulates phosphate and polyphosphate metabolism in Trypanosoma cruzi. Molecular Microbiology. 2015 Sep;97(5):911-25.
  • Niyogi S, Jimenez V, Gerard-Dias W, de Souza W, Miranda K, Docampo R.  2015. Rab32 is Essential for Maintaining Functional Acidocalcisomes and for Growth and Infectivity of Trypanosoma cruzi.  Journal of Cell Science. Jun 15;128(12):2363-73.
  • Jimenez V, Kemmerling U, Paredes R, Maya JD, Sosa MA and Galanti N. 2014. Natural sesquiterpene lactones induce programmed cell death in Trypanosoma cruzi: a new therapeutic target. Phytomedicine. Sep 25; 21(11):1411-8.
  • Pace D, Liu J, Jimenez V and Moreno SNJ. 2014. Store-operated calcium entry in the Apicomplexan parasite Toxoplasma gondii is nifedipine sensitive and results in significant enhancement of invasion-linked traits. J Biol Chem. Jul 11;289(28):19637-47.
  • Jimenez, V. 2014. Dealing with environmental challenges: mechanisms of adaptation in Trypanosoma cruzi. Res Microbiol. Apr 165(3):155-65.
  • Docampo R, Jimenez V, Lander N, Li ZH and Niyogi S. New Insights into the Roles of Acidocalcisomes and the Contractile Vacuole Complex in Osmoregulation in Protists. International Review of Cell and Molecular Biology. 2013;305:69-113.
  • Jimenez V and Docampo R. 2012. Molecular and electrophysiological characterization of a novel cation channel of Trypanosoma cruzi. PLoS Pathog. 2012 Jun;8(6):e1002750.
  • Docampo R, Jimenez V, King-Keller S, Li Z, Moreno SNJ. 2011. The Role of Acidocalcisomes in the Stress Response of Trypanosoma cruzi. Adv. Parasitol. 75: 307-24.
  • Ulrich PN#, Jimenez V# , Park M, Martins V, Atwood J, Moles K, Collins D, Rohloff P; Tarleton R, Moreno SNJ; Orlando R, Docampo R. 2011.  Identification of contractile vacuole proteins in Trypanosoma cruzi. PlosOne. 6(3) e18013. # Both authors contributed equally.
  • Jimenez V, Henriquez M, Galanti N, Riquelme G. 2011. Electrophysiological characterization of potassium conductive pathways in Trypanosoma cruzi. J Cell Biochem. 112 (4): 1093–1102.